GPCRProfiler Service
Safety & Disease Panels
Millipore is the premier provider of functional cell-based assays for GPCR screening and profiling. Whether you need to profile your lead compounds to evaluate potential side-effects or identify the therapeutic target for a biologically active molecule, GPCRProfiler Service Safety and Disease Panels can help you choose which GPCR targets will best address your research needs.
With GPCRProfiler Service, you receive:
- The flexibility to choose from 1 to 140 different receptors to screen against
- Your choice of 15 different service panels, including more than 57 distinct ligand families, 2 safety panels and 11 disease-focused panels
- A functional readout that includes both agonist and antagonist data
- The experience and knowledge of the Millipore scientists—the assay experts
| Panels | Subcategories, target tissues and/or description |
| FULL | Complete listing of receptors available on the GPCRProfiler service panel. |
| DIVERSITY | Diverse collection of receptors, including one representative member of each ligand family. |
| SAFETY PANELS | Broad Safety - A comprehensive panel of receptors with known or anticipated side-effects or liabilities.
Focused Safety - A focused panel of receptors known to be linked to common side-effects or liabilities. |
| DISEASE PANELS | Cancer
Cardiovascular - Heart, Thrombosis, Angiogenesis, Atherosclerosis, Hypertension, Flushing Digestive & Renal - GI, Renal, Liver, Urinary, Prostate Inflammation - Inflammation / Arthritis, Allergy, Itching, Dermatitis, Sepsis, Fever, Immunosuppression, Viral infection, HIV, MS, WHIM Metabolic - Appetite, Diabetes, Metabolic, Obesity, Dry mouth, Growth, Hyperthyroidism, Body Temperature Regulation, Osteoporosis, Calcium Homeostasis Neurological Disorders - Parkinson’s, Epilepsy, Cognition, Neuroprotection, Alzheimer’s, Nausea, MS Psychiatric Disorders - Psychosis, Depression, Mood / Anxiety, Addiction, Tourette’s, ADHD Reproduction - Reproduction, Fetal Development, Pre-term Labor, Newborn Health Respiratory - Respiratory, Asthma Sensory - Pain, Migraine, Vision, Macular Degeneration, Pupil Size, Glaucoma, Auditory, Smell Sleep - Sedation, Narcolepsy |
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| Download the datasheet to view the full list of GPCRProfiler Service Safety & Disease Panels To Place an Order for GPCRProfiler Service Safety & Disease Panels:
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Cross-Target Safety & Liability Screening
Millipore offers a unique cross-target service panel for early drug discovery screening against a liability-focused functional assay panel of GPCRs, ion channels, kinases and phosphatases.» Learn More...
